Potensi Sediaan Gel Ekstrak Daun Mangga (Mangifera indica L.) sebagai Penyembuh Luka Bakar Derajat II pada Tikus Putih Jantan (Rattus norvegicus)
Potensi Sediaan Gel Ekstrak Daun Mangga (Mangifera indica L.) sebagai Penyembuh Luka Bakar Derajat II pada Tikus Putih Jantan (Rattus norvegicus)
Abstract
Mango leaves (Mangifera indica L.) contain mangiferin compounds and components of secondary compounds such as alkaloids, flavonoids, saponins, steroids, polyphenols and tannins contained in mango leaves (Mangifera indica L.) which function as anti-inflammatory, anti-oxidant and antiseptic properties. can speed up the wound healing process. Mango leaves (Mangifera indica L.) are an alternative to traditional medicine for the healing process of burns. The development of drug dosage forms into gel preparations is the right choice and can be tested uSingh white rats (Rattus norvegicus). The purpose of this study was to determine the decrease in the diameter of second-degree burns in white rats (Rattus norvegicus) to mango leaf extract gel preparations (Mangifera indica L.) with concentrations of 5%, 10%, 15%, 20% and 25%. This research method includes experimental research with a simple completely randomized design (CRD). The sample in this study was some mango leaves (Mangifera indica L. Var Harumanis) in Lungbenda Palimanan Village, Cirebon. The sample technique uses a probability technique with simple random sampling. Data analysis uSingh the non-parametric Kruskal-Wallis test obtained a value of 0.095 > 0.05 which means that there is no significant or significant difference in each treatment group. The approach that is close to positive control is a concentration of 5% and 20% is a concentration that has a mean rank. the largest with the smallest diameter of 0.33 cm.
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